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Free-Mesothelioma-Injury.org
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For More Information
and Advice on
Breast Cancer Treatment
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Vitamin D and Calcium May Prevent Breast Cancer
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Vitamin D, calcium intakes are related to lower mammographic density.
Higher vitamin D and calcium intakes are related to lower mammographic
density in premenopausal women, but not in postmenopausal women.
"A better understanding of factors that affect breast density, one of
the strongest breast cancer risk indicators, may provide important clues
about breast cancer etiology and prevention," scientists in Canada
remarked. They conducted a study "to evaluate the association of vitamin
D and calcium, from food and/or supplements, to breast density in
premenopausal and postmenopausal women separately."
"A total of 777 premenopausal and 783 postmenopausal women recruited at
two radiology clinics in Quebec City, Canada, in 2001 to 2002, completed
a food frequency questionnaire to assess vitamin D and calcium."
S. Berube and colleagues wrote, "We assessed breast density from
screening mammograms using a computer-assisted method. Associations
between vitamin D or calcium and breast density were evaluated using
linear regression models. Adjusted means in breast density were assessed
according to the combined daily intakes of the two nutrients using
generalized linear models."
"In premenopausal women," the authors found, "total intakes of vitamin D
and calcium were inversely related to breast density (beta=-1.4; p=0.004
for vitamin D; beta=-0.8; p=0.0004 for calcium). In multivariate linear
regression, simultaneous increments in daily total intakes of 400 IU
vitamin D and 1,000 mg calcium were associated with an 8.5% (95%
confidence interval, 1.8.1) lower mean breast density."
The investigators noted, "The negative association between dietary
vitamin D intake and breast density tended to be stronger at higher
levels of calcium intake and vice versa. Among postmenopausal women,
intakes of vitamin D and calcium were not associated with breast
density."
They concluded, "These findings show that higher intakes of vitamin D
and calcium from food and supplements are related to lower levels of
breast density among premenopausal women. They suggest that increasing
intakes of vitamin D and calcium may represent a safe and inexpensive
strategy for breast cancer prevention."
Keywords: Quebec City, Quebec, Canada, Breast Cancer, Breast Cancer Risk
Factor, Diet and Nutrition, Vitamin D, Calcium, Women's Health |
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